Slc8a1 - solute carrier family 8 (sodium/calcium exchanger), member 1 Gene

Mus musculus

Also known as Ncx1; D930008O12Rik

Gene ID: 20541 | Gene type: protein coding

About Slc8a1

Summary

Enables ankyrin binding activity; calcium:sodium antiporter activity; and transmembrane transporter binding activity. Involved in several processes, including cellular response to caffeine; metal ion transport; and negative regulation of cytosolic calcium ion concentration. Acts upstream of or within several processes, including embryonic organ development; metal ion transport; and negative regulation of protein serine/threonine kinase activity. Located in several cellular components, including T-tubule; basolateral plasma membrane; and postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and nose. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human SLC8A1 (solute carrier family 8 member A1). [provided by Alliance of Genome Resources, Apr 2022]

Slc8a1 Products(3)

mRNA	Protein	Name
NM_001112798.2	NP_001106269.1	sodium/calcium exchanger 1 isoform B precursor
NM_001286684.1	NP_001273613.1	sodium/calcium exchanger 1 isoform C precursor
NM_011406.3	NP_035536.2	sodium/calcium exchanger 1 isoform A precursor

Protein Preferred Names

Protein Names

sodium/calcium exchanger 1

Na(+)/Ca(2+)-exchange protein 1	Na/Ca exchanger
solute carrier family 8 member 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13337	SLC8A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13340	SLC8B1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20598	Slc8b1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27106	Slc8b1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc8a1	NCBI	NCBI:6546

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