Smarcc1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 Gene

Also Known as Rsc8; SRG3; msp3; BAF155

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20588

Summary

Enables chromatin binding activity. Acts upstream of or within several processes, including Insulin Receptor signaling pathway; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and positive regulation of transcription by RNA polymerase II. Located in XY body and nucleus. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1). [provided by Alliance of Genome Resources, Apr 2022]

Smarcc1 Products (5)

mRNA Protein Name
NM_001413569.1 NP_001400498.1 SWI/SNF complex subunit SMARCC1 isoform 2
NM_001413570.1 NP_001400499.1 SWI/SNF complex subunit SMARCC1 isoform 3
NM_001413571.1 NP_001400500.1 SWI/SNF complex subunit SMARCC1 isoform 4
NM_001413572.1 NP_001400501.1 SWI/SNF complex subunit SMARCC1 isoform 5
NM_009211.3 NP_033237.2 SWI/SNF complex subunit SMARCC1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
17074803 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16287714 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within animal organ morphogenesis IMP
IMP: Inferred from mutant phenotype
11604513 MGI
acts upstream of or within insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
17074803 MGI
acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
22285184 MGI
acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
22285184 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
17074803 MGI
Cellular Component GO Annotation Evidence References Source
part of SWI/SNF complex IDA
IDA: Inferred from direct assay
16287714 MGI
part of SWI/SNF superfamily-type complex IDA
IDA: Inferred from direct assay
12368262 MGI
located in XY body IDA
IDA: Inferred from direct assay
16787967 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
11604513 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
16787967 MGI
part of nBAF complex IDA
IDA: Inferred from direct assay
17640523 MGI
part of npBAF complex IDA
IDA: Inferred from direct assay
17640523 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16787967 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SWI/SNF complex subunit SMARCC1

  • BRG1-associated factor 155

  • SWI/SNF complex 155 kDa subunit

  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1

  • SWI3-related protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13410 SMARCC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smarcc1 NCBI NCBI:6599