Smarcc1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 Gene

Mus musculus

Also known as Rsc8; SRG3; msp3; BAF155

Gene ID: 20588 | Gene type: protein coding

About Smarcc1

Summary

Enables chromatin binding activity. Acts upstream of or within several processes, including Insulin Receptor signaling pathway; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and positive regulation of transcription by RNA polymerase II. Located in XY body and nucleus. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1). [provided by Alliance of Genome Resources, Apr 2022]

Smarcc1 Products(5)

mRNA	Protein	Name
NM_001413569.1	NP_001400498.1	SWI/SNF complex subunit SMARCC1 isoform 2
NM_001413570.1	NP_001400499.1	SWI/SNF complex subunit SMARCC1 isoform 3
NM_001413571.1	NP_001400500.1	SWI/SNF complex subunit SMARCC1 isoform 4
NM_001413572.1	NP_001400501.1	SWI/SNF complex subunit SMARCC1 isoform 5
NM_009211.3	NP_033237.2	SWI/SNF complex subunit SMARCC1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	17074803	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	16287714	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within animal organ morphogenesis	IMP IMP: Inferred from mutant phenotype	11604513	MGI
acts upstream of or within insulin receptor signaling pathway	IDA IDA: Inferred from direct assay	17074803	MGI
acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process	IDA IDA: Inferred from direct assay	22285184	MGI
acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process	IMP IMP: Inferred from mutant phenotype	22285184	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	17074803	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of SWI/SNF complex	IDA IDA: Inferred from direct assay	16287714	MGI
part of SWI/SNF superfamily-type complex	IDA IDA: Inferred from direct assay	12368262	MGI
located in XY body	IDA IDA: Inferred from direct assay	16787967	MGI
located in intracellular anatomical structure	IDA IDA: Inferred from direct assay	11604513	MGI
located in male germ cell nucleus	IDA IDA: Inferred from direct assay	16787967	MGI
part of nBAF complex	IDA IDA: Inferred from direct assay	17640523	MGI
part of npBAF complex	IDA IDA: Inferred from direct assay	17640523	MGI
located in nucleus	IDA IDA: Inferred from direct assay	16787967	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

SWI/SNF complex subunit SMARCC1

BRG1-associated factor 155	SWI/SNF complex 155 kDa subunit
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1	SWI3-related protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13410	SMARCC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Smarcc1	NCBI	NCBI:6599

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