Snapin - SNAP-associated protein Gene

Also Known as 25kDa; Snapap; Bloc1s7; Snap25bp

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20615

Summary

Predicted to enable SNARE binding activity. Involved in anterograde synaptic vesicle transport; negative regulation of neuron projection development; and regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including lysosomal lumen acidification; terminal button organization; and vesicle organization. Located in acrosomal vesicle; cytosol; and manchette. Part of BLOC-1 complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human SNAPIN (SNAP associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Snapin Products (1)

mRNA Protein Name
NM_133854.3 NP_598615.1 SNARE-associated protein Snapin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102850 MGI
Biological Process GO Annotation Evidence References Source
involved in anterograde axonal transport IMP
IMP: Inferred from mutant phenotype
21998198 MGI
involved in anterograde synaptic vesicle transport IMP
IMP: Inferred from mutant phenotype
21998198 MGI
acts upstream of or within autophagosome maturation IMP
IMP: Inferred from mutant phenotype
20920792 MGI
acts upstream of or within chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
19217378 MGI
acts upstream of or within establishment of vesicle localization IMP
IMP: Inferred from mutant phenotype
20920792 MGI
acts upstream of or within late endosome to lysosome transport IMP
IMP: Inferred from mutant phenotype
20920792 MGI
acts upstream of or within lysosomal lumen acidification IMP
IMP: Inferred from mutant phenotype
20920792 MGI
acts upstream of or within lysosome organization IMP
IMP: Inferred from mutant phenotype
20920792 MGI
involved in negative regulation of neuron projection development IGI
IGI: Inferred from genetic interaction
21986494 MGI
acts upstream of or within neuron cellular homeostasis IMP
IMP: Inferred from mutant phenotype
20920792 MGI
acts upstream of or within protein maturation IMP
IMP: Inferred from mutant phenotype
20920792 MGI
acts upstream of or within protein-containing complex localization IMP
IMP: Inferred from mutant phenotype
20920792 MGI
involved in regulation of synaptic vesicle exocytosis IDA
IDA: Inferred from direct assay
19217378 MGI
involved in regulation of synaptic vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
19217378 MGI
acts upstream of or within retrograde axonal transport IMP
IMP: Inferred from mutant phenotype
20920792 MGI
acts upstream of or within synaptic vesicle fusion to presynaptic active zone membrane IMP
IMP: Inferred from mutant phenotype
19217378 MGI
acts upstream of or within synaptic vesicle maturation IMP
IMP: Inferred from mutant phenotype
19217378 MGI
acts upstream of or within terminal button organization IMP
IMP: Inferred from mutant phenotype
19217378 MGI
Cellular Component GO Annotation Evidence References Source
part of BLOC-1 complex IDA
IDA: Inferred from direct assay
15102850 MGI
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
31146259 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
31146259 MGI
located in cytosol IDA
IDA: Inferred from direct assay
15102850 MGI
located in manchette IDA
IDA: Inferred from direct assay
31146259 MGI
is active in microvesicle IDA
IDA: Inferred from direct assay
16760431 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SNARE-associated protein Snapin

  • BLOC-1 subunit 7

  • biogenesis of lysosome-related organelles complex 1 subunit 7

  • synaptosomal-associated protein 25 binding protein

  • synaptosomal-associated protein, 25 kDa, binding protein

Snapin Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Snapin Q9Z266 Csnk1d Rattus norvegicus Q06486-2
Y2H Array
17101137
Cross
Snapin Q9Z266 Csnk1d Rattus norvegicus Q06486-2
Anti Tag CoIP
17101137
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13481 SNAPIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snapin NCBI NCBI:23557