Snap91 - synaptosomal-associated protein 91 Gene

Also Known as 91kDa; AP180; F1-20; mKIAA0656

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20616

Summary

Enables 1-phosphatidylinositol binding activity; clathrin heavy chain binding activity; and protein kinase binding activity. Involved in clathrin coat assembly; neurotransmitter secretion; and synaptic vesicle budding from presynaptic endocytic zone membrane. Located in presynaptic endocytic zone and presynaptic endosome. Is extrinsic component of endosome membrane and extrinsic component of presynaptic endocytic zone membrane. Is expressed in several structures, including central nervous system; gut; limb; peripheral nervous system ganglion; and urinary system. Orthologous to human SNAP91 (synaptosome associated protein 91). [provided by Alliance of Genome Resources, Apr 2022]

Snap91 Products (8)

mRNA Protein Name
NM_001277982.2 NP_001264911.1 clathrin coat assembly protein AP180 isoform 3
NM_001277983.1 NP_001264912.1 clathrin coat assembly protein AP180 isoform 4
NM_001277985.1 NP_001264914.1 clathrin coat assembly protein AP180 isoform 5
NM_001277986.1 NP_001264915.1 clathrin coat assembly protein AP180 isoform 2
NM_001357768.1 NP_001344697.1 clathrin coat assembly protein AP180 isoform 6
NM_001357770.1 NP_001344699.1 clathrin coat assembly protein AP180 isoform 1
NM_001357772.1 NP_001344701.1 clathrin coat assembly protein AP180 isoform 7
NM_013669.2 NP_038697.1 clathrin coat assembly protein AP180 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables 1-phosphatidylinositol binding IDA
IDA: Inferred from direct assay
9045662 MGI
enables clathrin heavy chain binding IPI
IPI: Inferred from physical interaction
11102472 MGI
enables molecular adaptor activity EXP
EXP: Inferred from Experiment
20875424 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10428863 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
21307259 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
11102472 MGI
involved in clathrin coat assembly IDA
IDA: Inferred from direct assay
9045662 MGI
involved in clathrin coat assembly IMP
IMP: Inferred from mutant phenotype
10428863 MGI
involved in neurotransmitter secretion IMP
IMP: Inferred from mutant phenotype
11102472 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

clathrin coat assembly protein AP180

  • 91 kDa synaptosomal-associated protein

  • clathrin coat-associated protein AP180

  • phosphoprotein F1-20

  • synaptosomal-associated protein, 91 kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS13477 SNAP91 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snap91 NCBI NCBI:9892