Sox13 - SRY (sex determining region Y)-box 13 Gene

Mus musculus

Also known as Sox-13

Gene ID: 20668 | Gene type: protein coding

About Sox13

Summary

Enables DNA-binding transcription repressor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including gamma-delta T cell differentiation; positive regulation of cell differentiation; and spinal cord oligodendrocyte cell differentiation. Acts upstream of or within regulation of gamma-delta T cell differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including 1st branchial arch; alimentary system; central nervous system; early conceptus; and genitourinary system. Orthologous to human SOX13 (SRY-box transcription factor 13). [provided by Alliance of Genome Resources, Apr 2022]

Sox13 Products(1)

mRNA	Protein	Name
NM_011439.2	NP_035569.2	transcription factor SOX-13

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription repressor activity	IDA IDA: Inferred from direct assay	26525805	MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	9524265	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	17218525	MGI
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	9421502	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in gamma-delta T cell differentiation	IMP IMP: Inferred from mutant phenotype	17218525	MGI
involved in positive regulation of brown fat cell differentiation	IMP IMP: Inferred from mutant phenotype	27923061	MGI
involved in positive regulation of gamma-delta T cell differentiation	IMP IMP: Inferred from mutant phenotype	23562159	MGI
involved in regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	23562159	MGI
acts upstream of or within regulation of gamma-delta T cell differentiation	IDA IDA: Inferred from direct assay	21737317	MGI
involved in spinal cord oligodendrocyte cell differentiation	IGI IGI: Inferred from genetic interaction	26525805	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	10871192	MGI
located in nucleus	IDA IDA: Inferred from direct assay	9421502	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transcription factor SOX-13

SRY-box containing gene 13

mSox13

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13586	SOX13 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sox13	NCBI	NCBI:9580

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