Sox13 - SRY (sex determining region Y)-box 13 Gene
Also Known as Sox-13
Species: Mus musculus
Summary
Enables DNA-binding transcription repressor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including gamma-delta T cell differentiation; positive regulation of cell differentiation; and spinal cord oligodendrocyte cell differentiation. Acts upstream of or within regulation of gamma-delta T cell differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including 1st branchial arch; alimentary system; central nervous system; early conceptus; and genitourinary system. Orthologous to human SOX13 (SRY-box transcription factor 13). [provided by Alliance of Genome Resources, Apr 2022]
Sox13 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_011439.2 | NP_035569.2 | transcription factor SOX-13 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables DNA-binding transcription repressor activity |
IDA
IDA: Inferred from direct assay
|
26525805 | MGI |
| enables RNA polymerase II transcription regulatory region sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
9524265 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
17218525 | MGI |
| enables sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
9421502 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in gamma-delta T cell differentiation |
IMP
IMP: Inferred from mutant phenotype
|
17218525 | MGI |
| involved in positive regulation of brown fat cell differentiation |
IMP
IMP: Inferred from mutant phenotype
|
27923061 | MGI |
| involved in positive regulation of gamma-delta T cell differentiation |
IMP
IMP: Inferred from mutant phenotype
|
23562159 | MGI |
| involved in regulation of DNA-templated transcription |
IMP
IMP: Inferred from mutant phenotype
|
23562159 | MGI |
| acts upstream of or within regulation of gamma-delta T cell differentiation |
IDA
IDA: Inferred from direct assay
|
21737317 | MGI |
| involved in spinal cord oligodendrocyte cell differentiation |
IGI
IGI: Inferred from genetic interaction
|
26525805 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
10871192 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
9421502 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
transcription factor SOX-13 |
|