2. Gene
  3. SOX13 - SRY-box transcription factor 13 Gene

SOX13 - SRY-box transcription factor 13 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ICA12; Sox-13

Gene ID: 9580 | Gene type: protein coding

About SOX13

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:204,073,115-204,127,743 (from NCBI)

This gene has 10 transcripts (splice variants), 212 orthologues and 20 paralogues. Ubiquitous expression in placenta (RPKM 12.7), endometrium (RPKM 11.6) and 24 other tissues.

Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq, Jul 2008]

SOX13 Products(1)

mRNA Protein Name
NM_005686.3 NP_005677.2 transcription factor SOX-13

SOX13 Protein Structure

HMG_box

HMG_box: HMG (high mobility group) box (424 - 492)

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  • 622 a.a.
Protein Preferred Names Protein Names

transcription factor SOX-13

SRY (sex determining region Y)-box 13

Related Diseases

Diseases Alias
Type 1 Diabetes Mellitus 5

Diabetes Mellitus, Insulin-Dependent, 5

Latent Autoimmune Diabetes In Adults

IDDM5

Insulin-Dependent Diabetes Mellitus 5

T1D5

Lada

Type 1.5 Diabetes

Diabetes Mellitus, Insulin-Dependent, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13586 SOX13 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SOX13 VGNC VGNC:35142
Mus musculus SOX13 MGD MGI:98361
Rattus norvegicus SOX13 RGD RGD:1309674
Felis catus SOX13 VGNC VGNC:65579
Macaca mulatta SOX13 VGNC VGNC:77839
Canis familiaris SOX13 VGNC VGNC:46674