Sall3 - spalt like transcription factor 3 Gene
Also Known as Sal; Msal; Salt; Spalt; Msal-1; B130022O04Rik
Species: Mus musculus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within limb morphogenesis; negative regulation of smoothened signaling pathway; and olfactory bulb interneuron development. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; jaw; neural ectoderm; and sensory organ. Orthologous to human SALL3 (spalt like transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]
Sall3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001369133.1 | NP_001356062.1 | sal-like protein 3 isoform 1 |
| NM_178280.4 | NP_840064.2 | sal-like protein 3 isoform 2 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within forelimb morphogenesis |
IGI
IGI: Inferred from genetic interaction
|
19168674 | MGI |
| acts upstream of or within hindlimb morphogenesis |
IGI
IGI: Inferred from genetic interaction
|
19168674 | MGI |
| acts upstream of or within negative regulation of smoothened signaling pathway |
IGI
IGI: Inferred from genetic interaction
|
19168674 | MGI |
| acts upstream of or within olfactory bulb interneuron development |
IMP
IMP: Inferred from mutant phenotype
|
18260139 | MGI |
| acts upstream of smoothened signaling pathway |
IGI
IGI: Inferred from genetic interaction
|
19168674 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sal-like protein 3 |
|