Sall3 - spalt like transcription factor 3 Gene

Also Known as Sal; Msal; Salt; Spalt; Msal-1; B130022O04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20689

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within limb morphogenesis; negative regulation of smoothened signaling pathway; and olfactory bulb interneuron development. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; jaw; neural ectoderm; and sensory organ. Orthologous to human SALL3 (spalt like transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Sall3 Products (2)

mRNA Protein Name
NM_001369133.1 NP_001356062.1 sal-like protein 3 isoform 1
NM_178280.4 NP_840064.2 sal-like protein 3 isoform 2
Biological Process GO Annotation Evidence References Source
acts upstream of or within forelimb morphogenesis IGI
IGI: Inferred from genetic interaction
19168674 MGI
acts upstream of or within hindlimb morphogenesis IGI
IGI: Inferred from genetic interaction
19168674 MGI
acts upstream of or within negative regulation of smoothened signaling pathway IGI
IGI: Inferred from genetic interaction
19168674 MGI
acts upstream of or within olfactory bulb interneuron development IMP
IMP: Inferred from mutant phenotype
18260139 MGI
acts upstream of smoothened signaling pathway IGI
IGI: Inferred from genetic interaction
19168674 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sal-like protein 3

  • sal-like 3

  • spalt-like protein 3

Orthologs Information

Species Symbol Source ID
Homo sapiens Sall3 NCBI NCBI:27164