Fchsd2 - FCH and double SH3 domains 2 Gene

Also Known as NWK1; Sh3md3; mKIAA0769

Species: Mus musculus

Gene Type: protein coding
Gene ID: 207278

Summary

Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Involved in multi-organism membrane organization and positive regulation of actin filament polymerization. Located in stereocilium shaft. Is expressed in tail dorsal root ganglion and trigeminal ganglion. Orthologous to human FCHSD2 (FCH and double SH3 domains 2). [provided by Alliance of Genome Resources, Apr 2022]

Fchsd2 Products (2)

mRNA Protein Name
NM_001146010.1 NP_001139482.1 F-BAR and double SH3 domains protein 2 isoform 2
NM_199012.2 NP_950177.2 F-BAR and double SH3 domains protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23437151 MGI
Biological Process GO Annotation Evidence References Source
involved in membrane organization IMP
IMP: Inferred from mutant phenotype
23761074 MGI
involved in positive regulation of actin filament polymerization IDA
IDA: Inferred from direct assay
23437151 MGI
Cellular Component GO Annotation Evidence References Source
located in stereocilium shaft IDA
IDA: Inferred from direct assay
23437151 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-BAR and double SH3 domains protein 2

  • FCH and double SH3 domains protein 2

  • SH3 multiple domains 3

  • SH3 multiple domains protein 3

  • protein nervous wreck 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04837 FCHSD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fchsd2 NCBI NCBI:9873