Strbp - spermatid perinuclear RNA binding protein Gene

Mus musculus

Also known as Spnr; 6430510M02Rik; C230082I21Rik

Gene ID: 20744 | Gene type: protein coding

About Strbp

Summary

Enables double-stranded RNA binding activity; microtubule binding activity; and single-stranded RNA binding activity. Acts upstream of or within mechanosensory behavior and spermatid development. Located in manchette. Is expressed in central nervous system; dorsal root ganglion; metanephros; sensory organ; and trigeminal nerve. Orthologous to human STRBP (spermatid perinuclear RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Strbp Products(5)

mRNA	Protein	Name
NM_001355259.1	NP_001342188.1	spermatid perinuclear RNA-binding protein isoform a
NM_001379314.1	NP_001366243.1	spermatid perinuclear RNA-binding protein isoform a
NM_001379315.1	NP_001366244.1	spermatid perinuclear RNA-binding protein isoform a
NM_001379316.1	NP_001366245.1	spermatid perinuclear RNA-binding protein isoform c
NM_009261.4	NP_033287.2	spermatid perinuclear RNA-binding protein isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
NOT enables DNA binding	IDA IDA: Inferred from direct assay	7744952	MGI
enables double-stranded RNA binding	IDA IDA: Inferred from direct assay	7744952	MGI
enables microtubule binding	IDA IDA: Inferred from direct assay	9674995	MGI
enables single-stranded RNA binding	IDA IDA: Inferred from direct assay	7744952	MGI
enables tubulin binding	IDA IDA: Inferred from direct assay	9674995	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cell motility	IMP IMP: Inferred from mutant phenotype	11336498	MGI
acts upstream of or within mechanosensory behavior	IMP IMP: Inferred from mutant phenotype	11336498	MGI
acts upstream of or within spermatid development	IMP IMP: Inferred from mutant phenotype	11336498	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in manchette	IDA IDA: Inferred from direct assay	9674995	MGI
located in microtubule cytoskeleton	IDA IDA: Inferred from direct assay	7744952	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

spermatid perinuclear RNA-binding protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13962	STRBP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Strbp	NCBI	NCBI:55342

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