STRBP - spermatid perinuclear RNA binding protein Gene

Also Known as p74; SPNR; ILF3L; HEL162

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55342

About STRBP

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:123,109,494-123,268,586 (from NCBI)

This gene has 10 transcripts (splice variants), 281 orthologues and 14 paralogues. Broad expression in testis (RPKM 6.5), lymph node (RPKM 4.6) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within mechanosensory behavior and spermatid development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

STRBP Products (5)

mRNA Protein Name
NM_001171137.2 NP_001164608.1 spermatid perinuclear RNA-binding protein isoform 2
NM_001376106.1 NP_001363035.1 spermatid perinuclear RNA-binding protein isoform 1
NM_001376107.1 NP_001363036.1 spermatid perinuclear RNA-binding protein isoform 1
NM_001376109.1 NP_001363038.1 spermatid perinuclear RNA-binding protein isoform 3
NM_018387.5 NP_060857.2 spermatid perinuclear RNA-binding protein isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STRBP Protein Structure

DZF

DZF: DZF domain (87 - 333)

dsrm

dsrm: Double-stranded RNA binding motif (392 - 450)

dsrm

dsrm: Double-stranded RNA binding motif (515 - 574)

  • 0
  • 200
  • 400
  • 600
  • 672 a.a.
Protein Preferred Names Protein Names

spermatid perinuclear RNA-binding protein

  • epididymis luminal protein 162

STRBP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
STRBP Q96SI9 ZMAT4 Homo sapiens Q9H898-2
Y2H Prey Pooling
26871637
Intra
STRBP Q96SI9 ZMAT4 Homo sapiens Q9H898-2
Validated Y2H
26871637
Intra
STRBP Q96SI9 ZMAT4 Homo sapiens Q9H898-2
Y2H Array
26871637
Intra
STRBP Q96SI9 RBPMS2 Homo sapiens Q6ZRY4
Y2H Array
32296183
Intra
STRBP Q96SI9 RBPMS2 Homo sapiens Q6ZRY4
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 ADARB1 Homo sapiens P78563-4
Y2H Array
32296183
Intra
STRBP Q96SI9 ADARB1 Homo sapiens P78563-4
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 CAMK2G Homo sapiens Q13555-5
Y2H Array
32296183
Intra
STRBP Q96SI9 CAMK2G Homo sapiens Q13555-5
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 RBFOX1 Homo sapiens Q9NWB1-5
Validated Y2H
26871637
Intra
STRBP Q96SI9 RBFOX1 Homo sapiens Q9NWB1-5
Y2H Array
26871637
Intra
STRBP Q96SI9 RBFOX1 Homo sapiens Q9NWB1-5
Y2H Prey Pooling
26871637
Intra
STRBP Q96SI9 ZNF346 Homo sapiens Q9UL40
Validated Y2H
32296183
Intra
STRBP Q96SI9 ZNF346 Homo sapiens Q9UL40
Y2H Array
32296183
Intra
STRBP Q96SI9 ZNF346 Homo sapiens Q9UL40
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 STAU1 Homo sapiens O95793
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 STAU1 Homo sapiens O95793
Y2H Array
32296183
Intra
STRBP Q96SI9 PRKRA Homo sapiens O75569
Anti Tag CoIP
33961781
Intra
STRBP Q96SI9 PRKRA Homo sapiens O75569
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 PRKRA Homo sapiens O75569
Y2H Array
32296183
Intra
STRBP Q96SI9 HMGXB4 Homo sapiens Q9UGU5
Y2H Array
32296183
Intra
STRBP Q96SI9 HMGXB4 Homo sapiens Q9UGU5
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 HMGXB4 Homo sapiens Q9UGU5
Validated Y2H
32296183
Intra
STRBP Q96SI9 RBPMS Homo sapiens Q93062
Y2H Prey Pooling
25416956
Intra
STRBP Q96SI9 RBPMS Homo sapiens Q93062
Validated Y2H
25416956
Intra
STRBP Q96SI9 RBPMS Homo sapiens Q93062
Y2H Array
25416956
Intra
STRBP Q96SI9 RBPMS Homo sapiens Q93062-3
Y2H Prey Pooling
26871637
Intra
STRBP Q96SI9 RBPMS Homo sapiens Q93062-3
Validated Y2H
26871637
Intra
STRBP Q96SI9 RBPMS Homo sapiens Q93062-3
Y2H Array
26871637
Intra
STRBP Q96SI9 THAP1 Homo sapiens Q9NVV9
Y2H Prey Pooling
32296183
Intra
STRBP Q96SI9 THAP1 Homo sapiens Q9NVV9
Validated Y2H
32296183
Intra
STRBP Q96SI9 THAP1 Homo sapiens Q9NVV9
Y2H Array
25416956
Intra
STRBP Q96SI9 THAP1 Homo sapiens Q9NVV9
Y2H Array
32296183
Intra
STRBP Q96SI9 DAB1 Homo sapiens O75553
Validated Y2H
25416956
Intra
STRBP Q96SI9 TARBP2 Homo sapiens Q15633
Anti Tag CoIP
33961781
Intra
STRBP Q96SI9 TARBP2 Homo sapiens Q15633
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13962 STRBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus STRBP RGD RGD:620673
Bos taurus STRBP VGNC VGNC:35421
Macaca mulatta STRBP VGNC VGNC:78136
Mus musculus STRBP MGD MGI:104626
Canis familiaris STRBP VGNC VGNC:46942
Others STRBP NCBI