Phldb2 - pleckstrin homology like domain, family B, member 2 Gene

Also Known as LL5b; LL5beta; C820004H04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 208177

Summary

Predicted to be involved in several processes, including negative regulation of focal adhesion assembly; regulation of Cytoskeleton organization; and regulation of embryonic development. Predicted to be located in several cellular components, including cell leading edge; cytosol; and intermediate filament Cytoskeleton. Predicted to be active in basal cortex. Predicted to colocalize with focal adhesion. Orthologous to human PHLDB2 (pleckstrin homology like domain family B member 2). [provided by Alliance of Genome Resources, Apr 2022]

Phldb2 Products (3)

mRNA Protein Name
NM_001252442.1 NP_001239371.1 pleckstrin homology-like domain family B member 2 isoform 1
NM_001357078.1 NP_001344007.1 pleckstrin homology-like domain family B member 2 isoform 3
NM_153412.4 NP_700461.2 pleckstrin homology-like domain family B member 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27378169 MGI
Biological Process GO Annotation Evidence References Source
involved in cell migration IGI
IGI: Inferred from genetic interaction
27378169 MGI
involved in establishment of cell polarity IGI
IGI: Inferred from genetic interaction
27378169 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pleckstrin homology-like domain family B member 2

  • protein LL5-beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10446 PHLDB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Phldb2 NCBI NCBI:90102