Tor1aip1 - torsin A interacting protein 1 Gene

Also Known as LAP1; Lap1B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 208263

Summary

Predicted to enable several functions, including ATPase activator activity; ATPase binding activity; and lamin binding activity. Acts upstream of or within nuclear membrane organization and protein localization to nuclear envelope. Located in nuclear envelope. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2Y. Orthologous to human TOR1AIP1 (torsin 1A interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tor1aip1 Products (7)

mRNA Protein Name
NM_001160018.2 NP_001153490.1 torsin-1A-interacting protein 1 isoform 1
NM_001160019.2 NP_001153491.1 torsin-1A-interacting protein 1 isoform 3
NM_001405435.1 NP_001392364.1 torsin-1A-interacting protein 1 isoform 4
NM_001405436.1 NP_001392365.1 torsin-1A-interacting protein 1 isoform 3
NM_001405437.1 NP_001392366.1 torsin-1A-interacting protein 1 isoform 3
NM_001405438.1 NP_001392367.1 torsin-1A-interacting protein 1 isoform 3
NM_144791.3 NP_659040.2 torsin-1A-interacting protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15767459 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within nuclear membrane organization IGI
IGI: Inferred from genetic interaction
20457914 MGI
acts upstream of or within nuclear membrane organization IMP
IMP: Inferred from mutant phenotype
20457914 MGI
acts upstream of or within protein localization to nuclear envelope IMP
IMP: Inferred from mutant phenotype
20457914 MGI
Cellular Component GO Annotation Evidence References Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
15767459 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

torsin-1A-interacting protein 1

  • lamina-associated polypeptide 1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14904 TOR1AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tor1aip1 NCBI NCBI:26092