Slc26a7 - solute carrier family 26, member 7 Gene

Mus musculus

Gene ID: 208890 | Gene type: protein coding

About Slc26a7

Summary

Enables bicarbonate transmembrane transporter activity and Chloride Channel activity. Involved in bicarbonate transport and gastric acid secretion. Acts upstream of or within chloride transport. Located in basolateral plasma membrane. Is expressed in several structures, including alimentary system; brain; limb; respiratory system; and sensory organ. Orthologous to human SLC26A7 (solute carrier family 26 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc26a7 Products(1)

mRNA	Protein	Name
NM_145947.2	NP_666059.2	anion exchange transporter

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables bicarbonate transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	12736153	MGI
enables chloride channel activity	IDA IDA: Inferred from direct assay	15591059	MGI
enables chloride:bicarbonate antiporter activity	IDA IDA: Inferred from direct assay	12736153	MGI
enables chloride:bicarbonate antiporter activity	IMP IMP: Inferred from mutant phenotype	19723628	MGI
enables monoatomic anion channel activity	IMP IMP: Inferred from mutant phenotype	15591059	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in bicarbonate transport	IDA IDA: Inferred from direct assay	15591059	MGI
involved in bicarbonate transport	IMP IMP: Inferred from mutant phenotype	12736153	MGI
acts upstream of or within chloride transport	IDA IDA: Inferred from direct assay	15591059	MGI
involved in gastric acid secretion	IDA IDA: Inferred from direct assay	12736153	MGI
involved in gluconate transmembrane transport	IDA IDA: Inferred from direct assay	15591059	MGI
involved in iodide transport	IDA IDA: Inferred from direct assay	15591059	MGI
involved in iodide transport	IMP IMP: Inferred from mutant phenotype	30333321	MGI
acts upstream of or within monoatomic anion transport	IMP IMP: Inferred from mutant phenotype	15591059	MGI
involved in nitrate transmembrane transport	IDA IDA: Inferred from direct assay	15591059	MGI
involved in oxalate transport	IDA IDA: Inferred from direct assay	15591059	MGI
involved in sulfate transmembrane transport	IDA IDA: Inferred from direct assay	15591059	MGI
involved in thyroid hormone generation	IMP IMP: Inferred from mutant phenotype	30333321	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	12736153	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

anion exchange transporter

anion exchanger Slc26a7

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13141	SLC26A7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc26a7	NCBI	NCBI:115111

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