Ulk4 - unc-51-like kinase 4 Gene

Also Known as A730098P15; 4932415A06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 209012

Summary

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Acts upstream of or within several processes, including cerebrospinal fluid circulation; cilium organization; and nervous system development. Is expressed in brain. Used to study hydrocephalus. Orthologous to human ULK4 (unc-51 like kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Ulk4 Products (1)

mRNA Protein Name
NM_177589.3 NP_808257.2 serine/threonine-protein kinase ULK4

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within GABAergic neuron differentiation IMP
IMP: Inferred from mutant phenotype
29391390 MGI
acts upstream of or within adult behavior IMP
IMP: Inferred from mutant phenotype
29391390 MGI
acts upstream of or within adult walking behavior IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within axoneme assembly IMP
IMP: Inferred from mutant phenotype
27445138 MGI
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
27445138 MGI
acts upstream of or within central nervous system myelination IMP
IMP: Inferred from mutant phenotype
29034508 MGI
acts upstream of or within cerebral cortex development IMP
IMP: Inferred from mutant phenotype
34235142 MGI
acts upstream of or within cerebrospinal fluid circulation IMP
IMP: Inferred from mutant phenotype
27445138 MGI
acts upstream of or within ciliary basal body organization IMP
IMP: Inferred from mutant phenotype
27445138 MGI
acts upstream of or within cognition IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within corpus callosum development IMP
IMP: Inferred from mutant phenotype
24284070 MGI
acts upstream of or within dendritic spine development IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within epithelial cilium movement involved in extracellular fluid movement IMP
IMP: Inferred from mutant phenotype
21746835 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
21746835 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
29034508 MGI
acts upstream of or within layer formation in cerebral cortex IMP
IMP: Inferred from mutant phenotype
34235142 MGI
acts upstream of or within learning or memory IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within memory IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within motile cilium assembly IMP
IMP: Inferred from mutant phenotype
21746835 MGI
acts upstream of or within neurogenesis IMP
IMP: Inferred from mutant phenotype
27300315 MGI
acts upstream of or within neuroinflammatory response IMP
IMP: Inferred from mutant phenotype
29034508 MGI
acts upstream of or within neuronal stem cell division IMP
IMP: Inferred from mutant phenotype
27300315 MGI
acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within pyramidal neuron differentiation IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within regulation of protein-containing complex assembly IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within regulation of signal transduction IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within regulation of tau-protein kinase activity IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within sensory perception IMP
IMP: Inferred from mutant phenotype
35522199 MGI
acts upstream of or within smoothened signaling pathway IDA
IDA: Inferred from direct assay
34463328 MGI
acts upstream of or within social behavior IMP
IMP: Inferred from mutant phenotype
29391390 MGI
acts upstream of or within ventricular system development IMP
IMP: Inferred from mutant phenotype
21746835 MGI
Cellular Component GO Annotation Evidence References Source
is active in cilium IDA
IDA: Inferred from direct assay
34463328 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase ULK4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15458 ULK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ulk4 NCBI NCBI:54986