2. Gene
  3. Surf1 - surfeit gene 1 Gene

Surf1 - surfeit gene 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Surf-1; 0610010F23Rik

Gene ID: 20930 | Gene type: protein coding

About Surf1

Summary

Enables cytochrome-c oxidase activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. Is expressed in brain; embryo; and skeletal muscle. Used to study Leigh disease. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4K; Leigh disease; and cytochrome-c oxidase deficiency disease. Orthologous to human SURF1 (SURF1 cytochrome c oxidase assembly factor). [provided by Alliance of Genome Resources, Apr 2022]

Surf1 Products(2)

mRNA Protein Name
NM_001271724.1 NP_001258653.2 surfeit locus protein 1 isoform 2
NM_013677.2 NP_038705.2 surfeit locus protein 1 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables cytochrome-c oxidase activity IMP
IMP: Inferred from mutant phenotype
12566387 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

surfeit locus protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14042 SURF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Surf1 NCBI NCBI:6834