Surf1 - surfeit gene 1 Gene

Also Known as Surf-1; 0610010F23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20930

Summary

Enables cytochrome-c oxidase activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. Is expressed in brain; embryo; and skeletal muscle. Used to study Leigh disease. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4K; Leigh disease; and cytochrome-c oxidase deficiency disease. Orthologous to human SURF1 (SURF1 cytochrome c oxidase assembly factor). [provided by Alliance of Genome Resources, Apr 2022]

Surf1 Products (2)

mRNA Protein Name
NM_001271724.1 NP_001258653.2 surfeit locus protein 1 isoform 2
NM_013677.2 NP_038705.2 surfeit locus protein 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables cytochrome-c oxidase activity IMP
IMP: Inferred from mutant phenotype
12566387 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

surfeit locus protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14042 SURF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Surf1 NCBI NCBI:6834