Taf3 - TATA-box binding protein associated factor 3 Gene

Also Known as 140kDa; TAF140; TAFII140; TAFII-140; mTAFII140; 4933439M23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 209361

Summary

Enables p53 binding activity and transcription regulator inhibitor activity. Involved in negative regulation of DNA-binding transcription factor activity and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including eye; genitourinary system; heart; nervous system; and respiratory system. Orthologous to human TAF3 (TATA-box binding protein associated factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Taf3 Products (1)

mRNA Protein Name
NM_027748.3 NP_082024.2 transcription initiation factor TFIID subunit 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables p53 binding IPI
IPI: Inferred from physical interaction
18549481 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17704303 MGI
enables transcription regulator inhibitor activity IDA
IDA: Inferred from direct assay
18549481 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
18549481 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18549481 MGI
Cellular Component GO Annotation Evidence References Source
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
12665565 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription initiation factor TFIID subunit 3

  • 140 kDa TATA box-binding protein-associated factor

  • RNA polymerase II transcription factor, TFIID subunit

  • TAF(II)140

  • TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa

  • TBP-associated factor 3

  • transcription initiation fact

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14168 TAF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Taf3 NCBI NCBI:83860