2. Gene
  3. TAF3 - TATA-box binding protein associated factor 3 Gene

TAF3 - TATA-box binding protein associated factor 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TAF140; TAFII140; TAFII-140

Gene ID: 83860 | Gene type: protein coding

About TAF3

Cytogenetic location: 10p14 Genomic coordinates (GRCh38): 10:7,818,505-8,016,631 (from NCBI)

This gene has 8 transcripts (splice variants), 210 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 5.8), ovary (RPKM 3.8) and 25 other tissues.

Summary

The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009]

TAF3 Products(1)

mRNA Protein Name
NM_031923.4 NP_114129.1 transcription initiation factor TFIID subunit 3

TAF3 Protein Structure

Bromo_TP

Bromo_TP: Bromodomain associated (4 - 76)

PHD

PHD: PHD-finger (867 - 914)

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  • 929 a.a.
Protein Preferred Names Protein Names

transcription initiation factor TFIID subunit 3

140 kDa TATA box-binding protein-associated factor

Related Diseases

Diseases Alias
Lateral Meningocele Syndrome

Lehman Syndrome

Lms

LMNS

Meningocele, Lateral Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14168 TAF3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TAF3 MGD MGI:2388097
Felis catus TAF3 VGNC VGNC:65931
Macaca mulatta TAF3 VGNC VGNC:78147
Canis familiaris TAF3 VGNC VGNC:47081
Bos taurus TAF3 VGNC VGNC:35574
Rattus norvegicus TAF3 RGD RGD:2324594