Sycp1 - synaptonemal complex protein 1 Gene

Mus musculus

Also known as SCP1

Gene ID: 20957 | Gene type: protein coding

About Sycp1

Summary

Predicted to enable double-stranded DNA binding activity. Involved in reciprocal meiotic recombination and synaptonemal complex assembly. Acts upstream of or within meiosis I cell cycle process; regulation of protein localization; and sperm chromatin condensation. Located in central element; male germ cell nucleus; and transverse filament. Is expressed in brain and reproductive system. Orthologous to human SYCP1 (synaptonemal complex protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sycp1 Products(1)

mRNA	Protein	Name
NM_011516.2	NP_035646.2	synaptonemal complex protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	15944401	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within chiasma assembly	IGI IGI: Inferred from genetic interaction	22164254	MGI
involved in homologous chromosome pairing at meiosis	IMP IMP: Inferred from mutant phenotype	15937223	MGI
acts upstream of or within lateral element assembly	IGI IGI: Inferred from genetic interaction	22164254	MGI
acts upstream of or within meiotic DNA repair synthesis	IGI IGI: Inferred from genetic interaction	22164254	MGI
acts upstream of or within meiotic DNA repair synthesis	IMP IMP: Inferred from mutant phenotype	22164254	MGI
involved in reciprocal meiotic recombination	IMP IMP: Inferred from mutant phenotype	15937223	MGI
acts upstream of or within regulation of protein localization	IMP IMP: Inferred from mutant phenotype	16968740	MGI
acts upstream of or within sperm DNA condensation	IGI IGI: Inferred from genetic interaction	22164254	MGI
acts upstream of or within spermatogenesis	IGI IGI: Inferred from genetic interaction	22164254	MGI
involved in synaptonemal complex assembly	IDA IDA: Inferred from direct assay	15944401	MGI
acts upstream of or within synaptonemal complex assembly	IGI IGI: Inferred from genetic interaction	22164254	MGI
acts upstream of or within synaptonemal complex assembly	IMP IMP: Inferred from mutant phenotype	22164254	MGI
involved in synaptonemal complex assembly	IMP IMP: Inferred from mutant phenotype	15937223	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in autosome	IDA IDA: Inferred from direct assay	28031483	MGI
located in central element	IDA IDA: Inferred from direct assay	12584241	MGI
located in chromosome	IDA IDA: Inferred from direct assay	10794082	MGI
located in condensed nuclear chromosome	IDA IDA: Inferred from direct assay	22854038	MGI
located in male germ cell nucleus	IDA IDA: Inferred from direct assay	17696610	MGI
located in synaptonemal complex	IDA IDA: Inferred from direct assay	12815066	MGI
located in synaptonemal complex	IMP IMP: Inferred from mutant phenotype	15937223	MGI
located in transverse filament	IDA IDA: Inferred from direct assay	15870106	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

synaptonemal complex protein 1

SCP-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14070	SYCP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sycp1	NCBI	NCBI:6847

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