Sepsecs - Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase Gene

Also Known as SLA; SecS; D5Ertd135e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 211006

Summary

Enables tRNA binding activity. Involved in selenocysteine incorporation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; limb; musculoskeletal system; and respiratory system. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2D. Orthologous to human SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase). [provided by Alliance of Genome Resources, Apr 2022]

Sepsecs Products (2)

mRNA Protein Name
NM_001363463.1 NP_001350392.1 O-phosphoseryl-tRNA(Sec) selenium transferase isoform 2
NM_172490.4 NP_766078.1 O-phosphoseryl-tRNA(Sec) selenium transferase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16230358 MGI
enables tRNA binding IDA
IDA: Inferred from direct assay
16230358 MGI
Biological Process GO Annotation Evidence References Source
involved in selenocysteine incorporation IDA
IDA: Inferred from direct assay
16230358 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16230358 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16230358 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

O-phosphoseryl-tRNA(Sec) selenium transferase

  • UGA suppressor tRNA-associated protein

  • selenocysteinyl-tRNA(Sec) synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12680 SEPSECS Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sepsecs NCBI NCBI:51091