Inpp5a - inositol polyphosphate-5-phosphatase A Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 212111

Summary

Enables inositol-polyphosphate 5-phosphatase activity. Involved in negative regulation of neuron death. Located in dendrite. Is expressed in several structures, including craniocervical region bone; gonad; limb; nervous system; and sensory organ. Orthologous to human INPP5A (inositol polyphosphate-5-phosphatase A). [provided by Alliance of Genome Resources, Apr 2022]

Inpp5a Products (3)

mRNA Protein Name
NM_001127363.1 NP_001120835.1 inositol polyphosphate-5-phosphatase A isoform a
NM_001355162.1 NP_001342091.1 inositol polyphosphate-5-phosphatase A isoform c
NM_183144.3 NP_898967.2 inositol polyphosphate-5-phosphatase A isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables inositol-polyphosphate 5-phosphatase activity IMP
IMP: Inferred from mutant phenotype
26051944 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
26051944 MGI
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
26051944 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inositol polyphosphate-5-phosphatase A

  • 5PTase

  • type I inositol 1,4,5-trisphosphate 5-phosphatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06827 INPP5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21876 Inpp5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28393 Inpp5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Inpp5a NCBI NCBI:3632