2. Gene
  3. Rsph4a - radial spoke head 4 homolog A (Chlamydomonas) Gene

Rsph4a - radial spoke head 4 homolog A (Chlamydomonas) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rshl3; A230081C05

Gene ID: 212892 | Gene type: protein coding

About Rsph4a

Summary

Involved in radial spoke assembly. Acts upstream of or within maintenance of ciliary planar beating movement pattern. Located in cilium. Part of radial spoke head. Is expressed in lateral ventricle choroid plexus; lung epithelium; metencephalon part of 4th ventricle choroid plexus; and nasal cavity respiratory epithelium. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 11. Orthologous to human RSPH4A (radial spoke head component 4A). [provided by Alliance of Genome Resources, Apr 2022]

Rsph4a Products(1)

mRNA Protein Name
NM_001162957.1 NP_001156429.1 radial spoke head protein 4 homolog A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
30185526 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within epithelial cilium movement involved in extracellular fluid movement IMP
IMP: Inferred from mutant phenotype
26506310 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
26506310 MGI
acts upstream of or within maintenance of ciliary planar beating movement pattern IMP
IMP: Inferred from mutant phenotype
26506310 MGI
involved in radial spoke assembly IMP
IMP: Inferred from mutant phenotype
32203505 MGI
Cellular Component GO Annotation Evidence Reference Source
located in 9+2 motile cilium IDA
IDA: Inferred from direct assay
32203505 MGI
located in axoneme IDA
IDA: Inferred from direct assay
34871179 MGI
part of radial spoke head IDA
IDA: Inferred from direct assay
34871179 MGI
part of radial spoke head IMP
IMP: Inferred from mutant phenotype
26506310 MGI
part of radial spoke head 1 IDA
IDA: Inferred from direct assay
32203505 MGI
part of radial spoke head 2 IDA
IDA: Inferred from direct assay
32203505 MGI
part of radial spoke head 3 IDA
IDA: Inferred from direct assay
32203505 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

radial spoke head protein 4 homolog A

radial spoke head-like protein 3

radial spokehead-like 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12303 RSPH4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rsph4a NCBI NCBI:345895