Pm20d1 - peptidase M20 domain containing 1 Gene

Also Known as 4732466D17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 212933

Summary

Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including cellular amide catabolic process; energy homeostasis; and regulation of Oxidative Phosphorylation uncoupler activity. Located in extracellular space. Is expressed in embryo; embryo endoderm; and notochord. Orthologous to human PM20D1 (peptidase M20 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Pm20d1 Products (2)

mRNA Protein Name
NM_001357478.1 NP_001344407.1 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor
NM_178079.3 NP_835180.2 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IDA
IDA: Inferred from direct assay
27374330 MGI
Biological Process GO Annotation Evidence References Source
involved in adaptive thermogenesis IMP
IMP: Inferred from mutant phenotype
27374330 MGI
involved in amide biosynthetic process IDA
IDA: Inferred from direct assay
27374330 MGI
involved in amide catabolic process IDA
IDA: Inferred from direct assay
27374330 MGI
involved in amino acid metabolic process IDA
IDA: Inferred from direct assay
27374330 MGI
involved in cellular lipid metabolic process IDA
IDA: Inferred from direct assay
27374330 MGI
involved in energy homeostasis IMP
IMP: Inferred from mutant phenotype
27374330 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
27374330 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-fatty-acyl-amino acid synthase/hydrolase PM20D1

  • peptidase M20 domain-containing protein 1

  • probable carboxypeptidase PM20D1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139006 N-Oleoyl glutamine Inhibitor / Unkown
HY-RS10757 PM20D1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pm20d1 NCBI NCBI:148811