PM20D1 - peptidase M20 domain containing 1 Gene

Homo sapiens

Also known as Cps1

Gene ID: 148811 | Gene type: protein coding

About PM20D1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:205,828,025-205,850,132 (from NCBI)

This gene has 4 transcripts (splice variants), 215 orthologues and 3 paralogues. Biased expression in pancreas (RPKM 10.8), urinary bladder (RPKM 2.6) and 3 other tissues.

Summary

Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including amide biosynthetic process; cellular amide catabolic process; and negative regulation of neuron death. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PM20D1 Products(1)

mRNA	Protein	Name
NM_152491.5	NP_689704.4	N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor

PM20D1 Protein Structure

Peptidase_M20

M20_dimer

0
100
200
300
400
502 a.a.

Protein Preferred Names

Protein Names

N-fatty-acyl-amino acid synthase/hydrolase PM20D1

peptidase M20 domain-containing protein 1

Related Diseases

Diseases

Alias

Transient Arthritis

Norwegian Scabies

Crusted Scabies

Seven Year Itch

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-139006	N-Oleoyl glutamine	Inhibitor	/	Unkown
HY-RS10757	PM20D1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PM20D1	RGD	RGD:1564063
Mus musculus	PM20D1	MGD	MGI:2442939
Felis catus	PM20D1	VGNC	VGNC:64252
Bos taurus	PM20D1	VGNC	VGNC:33066
Canis familiaris	PM20D1	VGNC	VGNC:44727
Macaca mulatta	PM20D1	VGNC	VGNC:76118

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