Mylk3 - myosin light chain kinase 3 Gene

Also Known as MLCK; D830007F02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213435

Summary

Enables calmodulin-dependent protein kinase activity and Myosin light chain kinase activity. Involved in protein phosphorylation and sarcomere organization. Located in cytoplasm. Colocalizes with actin Cytoskeleton. Is expressed in heart atrium; heart ventricle; inner ear; and liver. Orthologous to human MYLK3 (Myosin light chain kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Mylk3 Products (2)

mRNA Protein Name
NM_001297612.1 NP_001284541.1 myosin light chain kinase 3 isoform 2
NM_175441.5 NP_780650.2 myosin light chain kinase 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables calcium/calmodulin-dependent protein kinase activity IDA
IDA: Inferred from direct assay
18202317 MGI
enables calcium/calmodulin-dependent protein kinase activity IDA
IDA: Inferred from direct assay
17885681 MGI
enables myosin light chain kinase activity IDA
IDA: Inferred from direct assay
17885681 MGI
Biological Process GO Annotation Evidence References Source
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
17885681 MGI
involved in sarcomere organization IDA
IDA: Inferred from direct assay
18202317 MGI
Cellular Component GO Annotation Evidence References Source
colocalizes with actin cytoskeleton IDA
IDA: Inferred from direct assay
18202317 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
18202317 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin light chain kinase 3

  • cardiac MLCK

  • cardiac-MyBP-C-associated Ca/CaM kinase

  • cardiac-specific myosin light chain kinase

  • putative myosin light chain kinase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08925 MYLK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22661 Mylk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29175 Mylk3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mylk3 NCBI NCBI:91807