Tal2 - T cell acute lymphocytic leukemia 2 Gene

Mus musculus

Also known as bHLHa19

Gene ID: 21350 | Gene type: protein coding

About Tal2

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within midbrain development; post-embryonic development; and thalamus development. Is expressed in several structures, including central nervous system; future midbrain; and genitourinary system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia and adult T-cell leukemia. Orthologous to human TAL2 (TAL bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tal2 Products(1)

mRNA	Protein	Name
NM_009317.4	NP_033343.1	T-cell acute lymphocytic leukemia protein 2 homolog

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within midbrain development	IMP IMP: Inferred from mutant phenotype	11071772	MGI
acts upstream of or within multicellular organism growth	IMP IMP: Inferred from mutant phenotype	11071772	MGI
acts upstream of or within post-embryonic development	IMP IMP: Inferred from mutant phenotype	11071772	MGI
acts upstream of or within thalamus development	IMP IMP: Inferred from mutant phenotype	11071772	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

T-cell acute lymphocytic leukemia protein 2 homolog

TAL-2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14190	TAL2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tal2	NCBI	NCBI:6887

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