Tarbp2 - TARBP2, RISC loading complex RNA binding subunit Gene

Also Known as Prbp; TRBP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21357

Summary

Predicted to enable several functions, including RNA binding activity; protein N-terminus binding activity; and protein homodimerization activity. Predicted to contribute to pre-miRNA binding activity. Acts upstream of or within several processes, including positive regulation of muscle cell differentiation; regulation of gene expression; and spermatid development. Part of RISC complex. Is expressed in brain and early embryo. Orthologous to human TARBP2 (TARBP2 subunit of RISC loading complex). [provided by Alliance of Genome Resources, Apr 2022]

Tarbp2 Products (2)

mRNA Protein Name
NM_001253795.1 NP_001240724.1 RISC-loading complex subunit TARBP2 isoform 2
NM_009319.3 NP_033345.2 RISC-loading complex subunit TARBP2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17452327 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
10369260 MGI
acts upstream of or within neural precursor cell proliferation IDA
IDA: Inferred from direct assay
28174252 MGI
acts upstream of or within positive regulation of muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
27159388 MGI
acts upstream of or within positive regulation of translation IMP
IMP: Inferred from mutant phenotype
10369260 MGI
acts upstream of or within regulation of miRNA processing IMP
IMP: Inferred from mutant phenotype
27159388 MGI
acts upstream of or within single fertilization IMP
IMP: Inferred from mutant phenotype
10369260 MGI
acts upstream of or within skeletal muscle tissue regeneration IMP
IMP: Inferred from mutant phenotype
27159388 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
10369260 MGI
Cellular Component GO Annotation Evidence References Source
part of RISC complex IDA
IDA: Inferred from direct assay
22503104 MGI
part of RISC-loading complex IPI
IPI: Inferred from physical interaction
20211135 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RISC-loading complex subunit TARBP2

  • PRM-1 RNA-binding protein

  • TAR (HIV) RNA binding protein 2

  • TAR RNA-binding protein 2

  • protamine-1 RNA-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14207 TARBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tarbp2 NCBI NCBI:6895