Tcp11 - t-complex protein 11 Gene

Also Known as Tcp-11; D17Ken1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21463

Summary

Involved in several processes, including protein kinase A signaling; regulation of cAMP-mediated signaling; and regulation of sperm capacitation. Located in acrosomal vesicle and sperm midpiece. Is expressed in testis. Orthologous to human TCP11 (t-complex 11). [provided by Alliance of Genome Resources, Apr 2022]

Tcp11 Products (11)

mRNA Protein Name
NM_001085555.2 NP_001079024.1 T-complex protein 11 isoform 2
NM_001357681.2 NP_001344610.1 T-complex protein 11 isoform 2
NM_001374620.1 NP_001361549.1 T-complex protein 11 isoform 3
NM_001374621.1 NP_001361550.1 T-complex protein 11 isoform 4
NM_001399994.1 NP_001386923.1 T-complex protein 11 isoform 1
NM_001399995.1 NP_001386924.1 T-complex protein 11 isoform 1
NM_001399996.1 NP_001386925.1 T-complex protein 11 isoform 2
NM_001399998.1 NP_001386927.1 T-complex protein 11 isoform 2
NM_001399999.1 NP_001386928.1 T-complex protein 11 isoform 4
NM_001400000.1 NP_001386929.1 T-complex protein 11 isoform 5
NM_013687.4 NP_038715.2 T-complex protein 11 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27105888 MGI
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
9820206 MGI
involved in negative regulation of exocytosis IMP
IMP: Inferred from mutant phenotype
9322250 MGI
involved in protein kinase A signaling IDA
IDA: Inferred from direct assay
27105888 MGI
involved in regulation of sperm capacitation IMP
IMP: Inferred from mutant phenotype
9322250 MGI
Cellular Component GO Annotation Evidence References Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
9322250 MGI
located in sperm flagellum IDA
IDA: Inferred from direct assay
9322250 MGI
located in sperm midpiece IDA
IDA: Inferred from direct assay
27105888 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-complex protein 11

  • testis-specific protein PBS13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14322 TCP11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14323 TCP11L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14324 TCP11L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tcp11 NCBI NCBI:6954