Mmp21 - matrix metallopeptidase 21 Gene

Also Known as b2b873Clo; b2b2458Clo

Species: Mus musculus

Gene Type: protein coding
Gene ID: 214766

Summary

This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading Enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. Mice harboring certain mutations in this gene exhibit congenital heart defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

Mmp21 Products (2)

mRNA Protein Name
NM_001320216.1 NP_001307145.1 matrix metalloproteinase-21 isoform 2 precursor
NM_152944.1 NP_694423.1 matrix metalloproteinase-21 isoform 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within coronary vasculature development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
involved in determination of heart left/right asymmetry IMP
IMP: Inferred from mutant phenotype
26437028 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
25807483 MGI
involved in determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
26437028 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IGI
IGI: Inferred from genetic interaction
24029230 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

matrix metalloproteinase-21

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08541 MMP21 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mmp21 NCBI NCBI:118856