Chtf18 - CTF18, chromosome transmission fidelity factor 18 Gene

Also Known as CTF18; Chl12; 6030457M03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 214901

Summary

Predicted to enable DNA binding activity. Predicted to contribute to DNA clamp loader activity and single-stranded DNA helicase activity. Acts upstream of or within cell development; meiotic nuclear division; and negative regulation of chromosome segregation. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and integumental system. Orthologous to human CHTF18 (chromosome transmission fidelity factor 18). [provided by Alliance of Genome Resources, Apr 2022]

Chtf18 Products (1)

mRNA Protein Name
NM_145409.2 NP_663384.2 chromosome transmission fidelity protein 18 homolog

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of chromosome segregation IMP
IMP: Inferred from mutant phenotype
23133398 MGI
acts upstream of or within germ cell development IMP
IMP: Inferred from mutant phenotype
23133398 MGI
acts upstream of or within male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
23133398 MGI
acts upstream of or within negative regulation of chromosome segregation IMP
IMP: Inferred from mutant phenotype
23133398 MGI
acts upstream of or within reciprocal meiotic recombination IMP
IMP: Inferred from mutant phenotype
23133398 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18250106 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
18250106 MGI
located in nucleus IDA
IDA: Inferred from direct assay
18250106 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromosome transmission fidelity protein 18 homolog

  • CTF18, chromosome transmission fidelity factor 18 homolog

  • Chl12 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02696 CHTF18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chtf18 NCBI NCBI:63922