CHTF18 - chromosome transmission fidelity factor 18 Gene

Homo sapiens

Also known as CHL12; Ctf18; RUVBL; C16orf41; C321D2.2; C321D2.3; C321D2.4

Gene ID: 63922 | Gene type: protein coding

About CHTF18

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:788,620-798,074 (from NCBI)

This gene has 20 transcripts (splice variants) and 160 orthologues. Broad expression in bone marrow (RPKM 7.1), testis (RPKM 6.3) and 24 other tissues.

Summary

This gene encodes a protein which is a component of a replication factor C (RFC) complex, which loads proliferating cell nuclear antigen (PCNA) on to DNA during the S phase of cell cycle. The encoded protein may interact with other proteins, including RFC complex 3, to form a clamp loader complex that plays a role in sister chromatid cohesion during metaphase-anaphase transition. [provided by RefSeq, Jan 2016]

CHTF18 Products(1)

mRNA	Protein	Name
NM_022092.3	NP_071375.1	chromosome transmission fidelity protein 18 homolog

CHTF18 Protein Structure

AAA

0
200
400
600
800
975 a.a.

Protein Preferred Names

Protein Names

chromosome transmission fidelity protein 18 homolog

CTF18, chromosome transmission fidelity factor 18 homolog

Related Diseases

Diseases

Alias

Roberts-Sc Phocomelia Syndrome

Roberts Syndrome	Sc Phocomelia Syndrome
RBS	Long Bone Deficiencies Associated With Cleft Lip-Palate
Sc Pseudothalidomide Syndrome	Appelt-Gerken-Lenz Syndrome
Pseudothalidomide Syndrome	Tetraphocomelia-Cleft Palate Syndrome
Hypomelia Hypotrichosis Facial Hemangioma Syndrome	Roberts Syndrome/Sc Phocomelia
Roberts Tetraphocomelia Syndrome	Sc Syndrome
Sc Phocomelia	Sc Disease
Sc	Hemoglobin Sc Disease

Cornelia De Lange Syndrome

De Lange Syndrome	Brachmann De Lange Syndrome
Brachmann-De Lange Syndrome	Cdls
Bdls	Typus Degenerativus Amstelodamensis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02696	CHTF18 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CHTF18	VGNC	VGNC:82344
Mus musculus	CHTF18	MGD	MGI:2384887
Macaca mulatta	CHTF18	VGNC	VGNC:71004
Rattus norvegicus	CHTF18	RGD	RGD:1310473
Canis familiaris	CHTF18	VGNC	VGNC:39260
Bos taurus	CHTF18	VGNC	VGNC:27352

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