2. Gene
  3. Plk5 - polo like kinase 5 Gene

Plk5 - polo like kinase 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 6330514A18Rik

Gene ID: 216166 | Gene type: protein coding

About Plk5

Chromosome 10: 80,192,293-80,201,323 forward strand.GRCm39:CM001003.3

This gene has 4 transcripts (splice variants), 98 orthologues and 4 paralogues. Biased expression in cerebellum adult (RPKM 19.2), cortex adult (RPKM 4.7) and 6 other tissues.

Summary

Predicted to enable ATP binding activity; metal ion binding activity; and protein kinase activity. Involved in several processes, including defense response to tumor cell; positive regulation of neuron projection development; and regulation of G1/S transition of mitotic cell cycle. Located in nucleolus. Is expressed in several structures, including central nervous system; eye; and ovary. Orthologous to human PLK5 (polo like kinase 5 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]

Plk5 Products(2)

mRNA Protein Name
NM_183152.4 NP_898975.2 inactive serine/threonine-protein kinase PLK5 isoform 1
NM_001347124.1 NP_001334053.1 inactive serine/threonine-protein kinase PLK5 isoform 2

Plk5 Protein Structure

STKc_PLK

STKc_PLK: cd14099 (24 - 278)

POLO_box_1

POLO_box_1: cd13118 (409 - 496)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 595 a.a.
Protein Preferred Names Protein Names

inactive serine/threonine-protein kinase PLK5

PLK-5

serine/threonine-protein kinase PLK5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10723 PLK5 Human Pre-designed siRNA Set A / Unkown
HY-RS10724 Plk5 Mouse Pre-designed siRNA Set A / Unkown
HY-RS10725 Plk5 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plk5 NCBI NCBI:126520