Slc5a8 - solute carrier family 5 (iodide transporter), member 8 Gene

Also Known as Ait; SMCT

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216225

Summary

Enables lactate transmembrane transporter activity; monocarboxylate:sodium symporter activity; and propionate transmembrane transporter activity. Acts upstream of or within propanoate transport and short-chain fatty acid import. Predicted to be located in brush border membrane. Is expressed in olfactory epithelium and rectum. Orthologous to human SLC5A8 (solute carrier family 5 member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slc5a8 Products (1)

mRNA Protein Name
NM_145423.2 NP_663398.2 sodium-coupled monocarboxylate transporter 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables lactate transmembrane transporter activity IDA
IDA: Inferred from direct assay
15322102 MGI
enables monocarboxylate:sodium symporter activity IDA
IDA: Inferred from direct assay
15322102 MGI
enables organic acid:sodium symporter activity IDA
IDA: Inferred from direct assay
15322102 MGI
enables propionate transmembrane transporter activity IDA
IDA: Inferred from direct assay
15322102 MGI
enables short-chain fatty acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
15322102 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within monocarboxylic acid transport IDA
IDA: Inferred from direct assay
15322102 MGI
involved in nicotinate transport IDA
IDA: Inferred from direct assay
15651982 MGI
acts upstream of or within propanoate transmembrane transport IDA
IDA: Inferred from direct assay
15322102 MGI
acts upstream of or within short-chain fatty acid transmembrane transport IDA
IDA: Inferred from direct assay
15322102 MGI
Cellular Component GO Annotation Evidence References Source
part of GINS complex IDA
IDA: Inferred from direct assay
20211600 MGI
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17245649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-coupled monocarboxylate transporter 1

  • electrogenic sodium monocarboxylate cotransporter

  • solute carrier family 5 member 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13294 SLC5A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc5a8 NCBI NCBI:160728