Acsl6 - acyl-CoA synthetase long-chain family member 6 Gene

Also Known as LACS; Facl6; Lacsl; mKIAA0837; A330035H04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216739

Summary

Enables long-chain fatty acid-CoA Ligase activity. Acts upstream of or within neuroblast proliferation. Located in mitochondrion. Is expressed in heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia and leukemia. Orthologous to human ACSL6 (acyl-CoA synthetase long chain family member 6). [provided by Alliance of Genome Resources, Apr 2022]

Acsl6 Products (4)

mRNA Protein Name
NM_001033597.1 NP_001028769.1 long-chain-fatty-acid--CoA ligase 6 isoform 2
NM_001033598.1 NP_001028770.1 long-chain-fatty-acid--CoA ligase 6 isoform 3
NM_001033599.1 NP_001028771.1 long-chain-fatty-acid--CoA ligase 6 isoform 4
NM_144823.4 NP_659072.3 long-chain-fatty-acid--CoA ligase 6 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
12767919 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12767919 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neuroblast proliferation IDA
IDA: Inferred from direct assay
12767919 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

long-chain-fatty-acid--CoA ligase 6

  • LACS 6

  • arachidonate--CoA ligase

  • fatty acid Coenzyme A ligase, long chain 6

  • long-chain acyl-CoA synthetase 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS20850 Acsl6 Mouse Pre-designed siRNA Set A / Unkown
HY-RS00204 ACSL6 Human Pre-designed siRNA Set A / Unkown
HY-RS27364 Acsl6 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acsl6 NCBI NCBI:23305