Trim58 - tripartite motif-containing 58 Gene

Also Known as Gm16; Gm1783

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216781

Summary

Enables dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein Ligase activity. Involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytoplasm. Orthologous to human TRIM58 (tripartite motif containing 58). [provided by Alliance of Genome Resources, Apr 2022]

Trim58 Products (1)

mRNA Protein Name
NM_001039047.2 NP_001034136.1 E3 ubiquitin-protein ligase TRIM58

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables dynein heavy chain binding IDA
IDA: Inferred from direct assay
25241935 MGI
enables dynein intermediate chain binding IDA
IDA: Inferred from direct assay
25241935 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
25241935 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of erythrocyte enucleation IMP
IMP: Inferred from mutant phenotype
25241935 MGI
involved in protein autoubiquitination IDA
IDA: Inferred from direct assay
25241935 MGI
involved in protein polyubiquitination IDA
IDA: Inferred from direct assay
25241935 MGI
involved in regulation of nuclear migration along microtubule IMP
IMP: Inferred from mutant phenotype
25241935 MGI
involved in ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
25241935 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM58

  • RING-type E3 ubiquitin transferase TRIM58

  • tripartite motif-containing protein 58

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15058 TRIM58 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim58 NCBI NCBI:25893