2. Gene
  3. Wrap53 - WD repeat containing, antisense to Trp53 Gene

Wrap53 - WD repeat containing, antisense to Trp53 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Wdr79

Gene ID: 216853 | Gene type: protein coding

About Wrap53

Summary

Predicted to enable several functions, including chaperone binding activity; Telomerase RNA binding activity; and ubiquitin protein Ligase binding activity. Involved in positive regulation of Telomerase activity. Predicted to be located in cytosol; nuclear body; and site of double-strand break. Predicted to be part of Telomerase holoenzyme complex. Predicted to be active in Cajal body. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 3; colorectal cancer; head and neck squamous cell carcinoma; lung non-small cell carcinoma; and ovarian Cancer. Orthologous to human WRAP53 (WD repeat containing antisense to TP53). [provided by Alliance of Genome Resources, Apr 2022]

Wrap53 Products(2)

mRNA Protein Name
NM_001364769.1 NP_001351698.1 telomerase Cajal body protein 1
NM_144824.3 NP_659073.1 telomerase Cajal body protein 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables RNA folding chaperone IDA
IDA: Inferred from direct assay
29804836 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

telomerase Cajal body protein 1

WD repeat containing, antisense to TP53

WD repeat domain 79

WD repeat-containing protein 79

WD repeat-containing protein WRAP53

WD40 repeat-containing protein antisense to TP53 gene homolog

WD40 repeat-containing protein encoded by RNA antisense to p

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15846 WRAP53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wrap53 NCBI NCBI:55135