Kctd11 - potassium channel tetramerisation domain containing 11 Gene

Also Known as Ren

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216858

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within negative regulation of neuroblast proliferation; negative regulation of smoothened signaling pathway; and positive regulation of neuron differentiation. Located in cytoplasm. Is expressed in several structures, including 1st branchial arch; central nervous system; ectoplacental cone; primitive streak; and sensory organ. Orthologous to human KCTD11 (Potassium Channel tetramerization domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]

Kctd11 Products (1)

mRNA Protein Name
NM_153143.4 NP_694783.1 BTB/POZ domain-containing protein KCTD11

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of neuroblast proliferation IDA
IDA: Inferred from direct assay
16148242 MGI
acts upstream of or within negative regulation of smoothened signaling pathway IDA
IDA: Inferred from direct assay
16148242 MGI
acts upstream of or within nervous system development IDA
IDA: Inferred from direct assay
12186855 MGI
acts upstream of neuroblast differentiation IDA
IDA: Inferred from direct assay
16148242 MGI
acts upstream of neuroblast proliferation IDA
IDA: Inferred from direct assay
16148242 MGI
acts upstream of neuron differentiation IDA
IDA: Inferred from direct assay
16148242 MGI
acts upstream of or within neuron differentiation IDA
IDA: Inferred from direct assay
12186855 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
16148242 MGI
acts upstream of or within regulation of cell population proliferation IDA
IDA: Inferred from direct assay
12186855 MGI
acts upstream of smoothened signaling pathway IDA
IDA: Inferred from direct assay
16148242 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12186855 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BTB/POZ domain-containing protein KCTD11

  • KCASH1 protein

  • RING-type E3 ubiquitin transferase KCTD11

  • RING-type E3 ubiquitin transferase subunit KCTD11

  • potassium channel tetramerization domain-containing protein 11

  • retinoic acid, EGF, and NGF upregulated

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07188 KCTD11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kctd11 NCBI NCBI:147040