FABP6 - fatty acid binding protein 6 Gene
Also Known as ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
Species: Homo sapiens
About FABP6
This gene has 4 transcripts (splice variants), 261 orthologues and 15 paralogues. Restricted expression toward small intestine (RPKM 820.3).
Summary
This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and Other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]
FABP6 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001040442.1 | NP_001035532.1 | gastrotropin isoform 1 |
| NM_001130958.2 | NP_001124430.1 | gastrotropin isoform 1 |
| NM_001445.3 | NP_001436.1 | gastrotropin isoform 2 |
FABP6 Protein Structure
Lipocalin_7: Lipocalin / cytosolic fatty-acid binding protein family (1 - 128)
- 0
- 100
- 128 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
gastrotropin |
|
Recombinant FABP6 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P70160 | Gastrotropin/FABP6 Protein, Human (His) | AAH22489.1 (M1-A128) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Colorectal Adenocarcinoma |
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| Progressive Familial Intrahepatic Cholestasis |
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| Anal Gland Neoplasm |
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| Intrahepatic Cholestasis |
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| Barrett Esophagus |
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| Intrahepatic Cholestasis Of Pregnancy |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Felis catus | FABP6 | VGNC | VGNC:102199 |
| Mus musculus | FABP6 | MGD | MGI:96565 |
| Canis familiaris | FABP6 | VGNC | VGNC:40562 |
| Macaca mulatta | FABP6 | VGNC | VGNC:72469 |
| Rattus norvegicus | FABP6 | RGD | RGD:2592 |
| Bos taurus | FABP6 | VGNC | VGNC:28698 |
| Others | FABP6 | NCBI |