G2e3 - G2/M-phase specific E3 ubiquitin ligase Gene

Also Known as mKIAA1333; 9030416F18; 6030408C04Rik; D930034K21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217558

Summary

Enables ubiquitin protein Ligase activity. Acts upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; epithelium; limb; liver; and male reproductive gland or organ. Orthologous to human G2E3 (G2/M-phase specific E3 ubiquitin protein Ligase). [provided by Alliance of Genome Resources, Apr 2022]

G2e3 Products (3)

mRNA Protein Name
NM_001015099.2 NP_001015099.2 G2/M phase-specific E3 ubiquitin-protein ligase isoform 1
NM_001167963.1 NP_001161435.1 G2/M phase-specific E3 ubiquitin-protein ligase isoform 2
NM_001167964.1 NP_001161436.1 G2/M phase-specific E3 ubiquitin-protein ligase isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
18511420 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within blastocyst development IMP
IMP: Inferred from mutant phenotype
18511420 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
18511420 MGI
acts upstream of or within protein polyubiquitination IDA
IDA: Inferred from direct assay
18511420 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G2/M phase-specific E3 ubiquitin-protein ligase

  • G2/M phase-specific HECT-type E3 ubiquitin transferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05188 G2E3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens G2e3 NCBI NCBI:55632