2. Gene
  3. Mlh3 - mutL homolog 3 Gene

Mlh3 - mutL homolog 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 217716 | Gene type: protein coding

About Mlh3

Summary

Enables centromeric DNA binding activity and chromatin binding activity. Acts upstream of or within meiotic nuclear division; mismatch repair; and protein localization. Located in chiasma; male germ cell nucleus; and synaptonemal complex. Part of mismatch repair complex. Is expressed in brain; early conceptus; ileum; reproductive system; and trigeminal nerve. Human ortholog(s) of this gene implicated in Lynch syndrome; colorectal cancer; endometrial cancer; and hereditary nonpolyposis colorectal Cancer type 7. Orthologous to human MLH3 (mutL homolog 3). [provided by Alliance of Genome Resources, Apr 2022]

Mlh3 Products(2)

mRNA Protein Name
NM_001304475.1 NP_001291404.1 DNA mismatch repair protein Mlh3
NM_175337.2 NP_780546.1 DNA mismatch repair protein Mlh3
Protein Preferred Names Protein Names

DNA mismatch repair protein Mlh3

mutL 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08490 MLH3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mlh3 NCBI NCBI:27030