Mlh3 - mutL homolog 3 Gene
Species: Mus musculus
Gene Type: protein coding
Gene ID: 217716
Summary
Enables centromeric DNA binding activity and chromatin binding activity. Acts upstream of or within meiotic nuclear division; mismatch repair; and protein localization. Located in chiasma; male germ cell nucleus; and synaptonemal complex. Part of mismatch repair complex. Is expressed in brain; early conceptus; ileum; reproductive system; and trigeminal nerve. Human ortholog(s) of this gene implicated in Lynch syndrome; colorectal cancer; endometrial cancer; and hereditary nonpolyposis colorectal Cancer type 7. Orthologous to human MLH3 (mutL homolog 3). [provided by Alliance of Genome Resources, Apr 2022]
Mlh3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001304475.1 | NP_001291404.1 | DNA mismatch repair protein Mlh3 |
| NM_175337.2 | NP_780546.1 | DNA mismatch repair protein Mlh3 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
DNA mismatch repair protein Mlh3 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS08490 | MLH3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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