Gmds - GDP-mannose 4, 6-dehydratase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 218138

Summary

Predicted to enable GDP-mannose 4,6-dehydratase activity. Predicted to be involved in 'de novo' GDP-L-fucose biosynthetic process and GDP-mannose metabolic process. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; ear; nervous system; respiratory system; and skeleton. Human ortholog(s) of this gene implicated in open-angle glaucoma. Orthologous to human GMDS (GDP-mannose 4,6-dehydratase). [provided by Alliance of Genome Resources, Apr 2022]

Gmds Products (1)

mRNA Protein Name
NM_146041.2 NP_666153.1 GDP-mannose 4,6 dehydratase

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GDP-mannose 4,6-dehydratase activity IDA
IDA: Inferred from direct assay
29033318 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
29033318 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GDP-mannose 4,6 dehydratase

  • GDP-D-mannose dehydratase

  • GMD

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N7389A GDP-D-mannose disodium 99.97% Unkown
HY-RS05515 GMDS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21350 Gmds Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27869 Gmds Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gmds NCBI NCBI:2762