Ptpdc1 - protein tyrosine phosphatase domain containing 1 Gene

Also Known as Naa-1; Ptpcd1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 218232

Summary

The protein encoded by this gene is a centrosomal mitotic Phosphatase. This protein has been implicated in centrosomal duplication and cytokinesis. In addition, knockdown of expression levels in non-cycling cells results in extra long cilia, suggesting that this protein may function in regulating cilia length independent of a function in cell cycle control. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]

Ptpdc1 Products (3)

mRNA Protein Name
NM_001301781.1 NP_001288710.1 protein tyrosine phosphatase domain-containing protein 1 isoform 1
NM_001374755.1 NP_001361684.1 protein tyrosine phosphatase domain-containing protein 1 isoform 3
NM_207232.2 NP_997115.1 protein tyrosine phosphatase domain-containing protein 1 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
21289087 MGI
acts upstream of or within smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
21289087 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein tyrosine phosphatase domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11413 PTPDC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21917 Ptpdc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptpdc1 NCBI NCBI:138639