Ttc5 - tetratricopeptide repeat domain 5 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 219022

Summary

Enables DNA binding activity and chromatin binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Orthologous to human TTC5 (tetratricopeptide repeat domain 5). [provided by Alliance of Genome Resources, Apr 2022]

Ttc5 Products (3)

mRNA Protein Name
NM_001080949.2 NP_001074418.1 tetratricopeptide repeat protein 5 isoform a
NM_001360545.1 NP_001347474.1 tetratricopeptide repeat protein 5 isoform c
NM_177625.4 NP_808293.1 tetratricopeptide repeat protein 5 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
22362889 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
22362889 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11511361 MGI
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IDA
IDA: Inferred from direct assay
18833288 MGI
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
15448695 MGI
involved in cellular response to starvation IMP
IMP: Inferred from mutant phenotype
30420355 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
22362889 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22362889 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
30420355 MGI
located in cytosol IDA
IDA: Inferred from direct assay
15448695 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
25168243 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15448695 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tetratricopeptide repeat protein 5

  • TPR repeat protein 5

  • protein Strap

  • stress-responsive activator of p300

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15216 TTC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttc5 NCBI NCBI:91875