2. Gene
  3. Pip4p1 - phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 Gene

Pip4p1 - phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tmem55b

Gene ID: 219024 | Gene type: protein coding

About Pip4p1

Summary

Predicted to enable phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Involved in positive regulation of TORC1 signaling and proton-transporting V-type ATPase complex assembly. Located in bounding membrane of organelle and plasma membrane. Orthologous to human PIP4P1 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pip4p1 Products(4)

mRNA Protein Name
NM_001033271.5 NP_001028443.1 type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform 1
NM_001310505.1 NP_001297434.1 type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform 2
NM_001310506.1 NP_001297435.1 type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform 3
NM_001310507.1 NP_001297436.1 type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform 4
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
29644770 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of TORC1 signaling IMP
IMP: Inferred from mutant phenotype
29644770 MGI
involved in proton-transporting V-type ATPase complex assembly IMP
IMP: Inferred from mutant phenotype
29644770 MGI
Cellular Component GO Annotation Evidence Reference Source
located in late endosome membrane IDA
IDA: Inferred from direct assay
29378918 MGI
located in lysosomal membrane IDA
IDA: Inferred from direct assay
29644770 MGI
located in phagocytic vesicle membrane IDA
IDA: Inferred from direct assay
29378918 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
29378918 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

PtdIns-4,5-P(2) 4-phosphatase type I

ptdIns-4,5-P2 4-Ptase I

transmembrane protein 55b

type 1 PtdIns-4,5-P2 4-Ptase

type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10565 PIP4P1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pip4p1 NCBI NCBI:90809