Akap11 - A kinase (PRKA) anchor protein 11 Gene

Also Known as Gm80; PRKA11; AKAP220; mKIAA0629; 6330501D17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 219181

Summary

Enables protein kinase A regulatory subunit binding activity. Acts upstream of or within cortical actin Cytoskeleton organization; protein localization to endosome; and renal water homeostasis. Predicted to be located in several cellular components, including cytosol; nucleolus; and peroxisome. Predicted to be part of protein-containing complex. Is expressed in several structures, including alimentary system; eye; genitourinary system; immune system; and nervous system. Orthologous to human AKAP11 (A-kinase anchoring protein 11). [provided by Alliance of Genome Resources, Apr 2022]

Akap11 Products (2)

mRNA Protein Name
NM_001164503.1 NP_001157975.1 A-kinase anchor protein 11 isoform 1
NM_001346784.1 NP_001333713.1 A-kinase anchor protein 11 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30026308 MGI
enables protein kinase A regulatory subunit binding IPI
IPI: Inferred from physical interaction
21502359 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cortical actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
27402760 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
27402760 MGI
acts upstream of or within protein localization to endosome IDA
IDA: Inferred from direct assay
21502359 MGI
acts upstream of or within protein localization to endosome IMP
IMP: Inferred from mutant phenotype
21502359 MGI
acts upstream of or within renal water homeostasis IMP
IMP: Inferred from mutant phenotype
27402760 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A-kinase anchor protein 11

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00514 AKAP11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akap11 NCBI NCBI:11215