Tnnc1 - troponin C, cardiac/slow skeletal Gene
Also Known as TnC; cTnC; cTnI; tncc
Species: Mus musculus
Summary
Enables actin filament binding activity. Involved in regulation of ATPase activity and regulation of muscle filament sliding speed. Acts upstream of or within transition between fast and slow fiber. Predicted to be located in contractile fiber. Predicted to be part of cardiac Troponin complex. Is expressed in several structures, including alimentary system; heart; liver; metanephros; and skeletal muscle. Used to study hypertrophic cardiomyopathy 13. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Z; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 13. Orthologous to human TNNC1 (troponin C1, slow skeletal and cardiac type). [provided by Alliance of Genome Resources, Apr 2022]
Tnnc1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_009393.4 | NP_033419.1 | troponin C, slow skeletal and cardiac muscles |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables actin filament binding |
IDA
IDA: Inferred from direct assay
|
8785301 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in regulation of ATP-dependent activity |
IDA
IDA: Inferred from direct assay
|
8785301 | MGI |
| involved in regulation of muscle filament sliding speed |
IMP
IMP: Inferred from mutant phenotype
|
10747195 | MGI |
| acts upstream of or within transition between fast and slow fiber |
IDA
IDA: Inferred from direct assay
|
18978355 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
troponin C, slow skeletal and cardiac muscles |
|