Dedd - death effector domain-containing Gene

Also Known as DEFT; KE05; FLDED1; Dedpro1; CASP8IP1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21945

Summary

Enables DNA binding activity. Acts upstream of or within decidualization; extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of nitrogen compound metabolic process. Located in cytoplasm and nucleolus. Is expressed in central nervous system and retina. Orthologous to human DEDD (death effector domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Dedd Products (6)

mRNA Protein Name
NM_001128609.1 NP_001122081.1 death effector domain-containing protein
NM_001357550.1 NP_001344479.1 death effector domain-containing protein
NM_001357551.1 NP_001344480.1 death effector domain-containing protein
NM_001357552.1 NP_001344481.1 death effector domain-containing protein
NM_001357553.1 NP_001344482.1 death effector domain-containing protein
NM_011615.3 NP_035745.3 death effector domain-containing protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
9774341 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9774341 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within decidualization IMP
IMP: Inferred from mutant phenotype
21135503 MGI
acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors IDA
IDA: Inferred from direct assay
9774341 MGI
acts upstream of or within negative regulation of protein catabolic process IMP
IMP: Inferred from mutant phenotype
21135503 MGI
acts upstream of or within negative regulation of transcription of nucleolar large rRNA by RNA polymerase I IDA
IDA: Inferred from direct assay
9774341 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9774341 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
9774341 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

death effector domain-containing protein

  • tumor necrosis factor (ligand) superfamily, member 19

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03669 DEDD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03670 DEDD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dedd NCBI NCBI:9191