Pglyrp1 - peptidoglycan recognition protein 1 Gene

Also Known as PGRP; Tag7; Tasg7; PGRP-S; Pglyrp; Tnfsf3l

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21946

Summary

Predicted to enable peptidoglycan binding activity and peptidoglycan immune receptor activity. Acts upstream of or within several processes, including negative regulation of inflammatory response; negative regulation of interferon-gamma production; and negative regulation of natural killer cell differentiation involved in immune response. Predicted to be located in cytoplasm and extracellular space. Is expressed in alimentary system; craniocervical region bone; genitourinary system; liver; and respiratory system. Orthologous to human PGLYRP1 (peptidoglycan recognition protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pglyrp1 Products (1)

mRNA Protein Name
NM_009402.2 NP_033428.1 peptidoglycan recognition protein 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within biological process involved in interaction with host IMP
IMP: Inferred from mutant phenotype
20709292 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
19218085 MGI
acts upstream of or within negative regulation of natural killer cell differentiation involved in immune response IMP
IMP: Inferred from mutant phenotype
20709292 MGI
acts upstream of or within negative regulation of type II interferon production IMP
IMP: Inferred from mutant phenotype
20709292 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidoglycan recognition protein 1

  • cytokine tag7

Recombinant Pglyrp1 Proteins

Cat. No. Product Name Accession Purity
HY-P76543 PGLYRP1/PGRP-S Protein, Mouse (HEK293, His) O88593 (F19-E182) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78338 PGLYRP1/PGRP-S Protein, Mouse (HEK293, Fc) O88593 (F19-E182) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10387 PGLYRP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19093 Pglyrp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25583 Pglyrp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pglyrp1 NCBI NCBI:8993