2. Gene
  3. Tnp2 - transition protein 2 Gene

Tnp2 - transition protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TP2; Tp-2

Gene ID: 21959 | Gene type: protein coding

About Tnp2

Summary

Predicted to enable zinc ion binding activity. Involved in positive regulation of protein processing and spermatogenesis, exchange of chromosomal proteins. Acts upstream of or within flagellated sperm motility; single fertilization; and spermatogenesis. Located in nucleus. Part of nucleosome. Is expressed in spermatid and testis. Orthologous to human TNP2 (transition protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Tnp2 Products(1)

mRNA Protein Name
NM_013694.4 NP_038722.3 nuclear transition protein 2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within acrosome reaction IMP
IMP: Inferred from mutant phenotype
11385107 MGI
acts upstream of or within binding of sperm to zona pellucida IGI
IGI: Inferred from genetic interaction
15685642 MGI
acts upstream of or within flagellated sperm motility IGI
IGI: Inferred from genetic interaction
15051954 MGI
acts upstream of or within penetration of zona pellucida IMP
IMP: Inferred from mutant phenotype
11385107 MGI
involved in positive regulation of protein processing IMP
IMP: Inferred from mutant phenotype
28366643 MGI
involved in sperm DNA condensation IMP
IMP: Inferred from mutant phenotype
15083521 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
11385107 MGI
Cellular Component GO Annotation Evidence Reference Source
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
14680821 MGI
part of nucleosome IDA
IDA: Inferred from direct assay
28366643 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10369260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear transition protein 2

transition protein 2 (alt.)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14858 TNP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnp2 NCBI NCBI:7142