Tnp2 - transition protein 2 Gene

Also Known as TP2; Tp-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21959

Summary

Predicted to enable zinc ion binding activity. Involved in positive regulation of protein processing and spermatogenesis, exchange of chromosomal proteins. Acts upstream of or within flagellated sperm motility; single fertilization; and spermatogenesis. Located in nucleus. Part of nucleosome. Is expressed in spermatid and testis. Orthologous to human TNP2 (transition protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Tnp2 Products (1)

mRNA Protein Name
NM_013694.4 NP_038722.3 nuclear transition protein 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within acrosome reaction IMP
IMP: Inferred from mutant phenotype
11385107 MGI
acts upstream of or within binding of sperm to zona pellucida IGI
IGI: Inferred from genetic interaction
15685642 MGI
acts upstream of or within flagellated sperm motility IGI
IGI: Inferred from genetic interaction
15051954 MGI
acts upstream of or within penetration of zona pellucida IMP
IMP: Inferred from mutant phenotype
11385107 MGI
involved in positive regulation of protein processing IMP
IMP: Inferred from mutant phenotype
28366643 MGI
involved in sperm DNA condensation IMP
IMP: Inferred from mutant phenotype
15083521 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
11385107 MGI
Cellular Component GO Annotation Evidence References Source
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
14680821 MGI
part of nucleosome IDA
IDA: Inferred from direct assay
28366643 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10369260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear transition protein 2

  • transition protein 2 (alt.)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14858 TNP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnp2 NCBI NCBI:7142