Tulp3 - tubby-like protein 3 Gene

Also Known as 2310022L06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22158

Summary

Predicted to enable several functions, including enzyme binding activity; intraciliary transport particle A binding activity; and phosphatidylinositol binding activity. Acts upstream of or within several processes, including animal organ development; nervous system development; and regulation of signal transduction. Located in axoneme. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and respiratory system. Used to study polycystic kidney disease. Orthologous to human TULP3 (TUB like protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Tulp3 Products (1)

mRNA Protein Name
NM_011657.2 NP_035787.1 tubby-related protein 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
19334287 MGI
acts upstream of or within bone development IMP
IMP: Inferred from mutant phenotype
11406614 MGI
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
11406614 MGI
acts upstream of or within bronchus morphogenesis IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of or within central nervous system neuron differentiation IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of or within dorsal/ventral neural tube patterning IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of or within embryonic camera-type eye development IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of or within embryonic digit morphogenesis IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of or within embryonic neurocranium morphogenesis IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of or within ganglion development IMP
IMP: Inferred from mutant phenotype
11406614 MGI
acts upstream of or within limb development IGI
IGI: Inferred from genetic interaction
19223390 MGI
acts upstream of or within limb development IMP
IMP: Inferred from mutant phenotype
19223390 MGI
acts upstream of or within negative regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19223390 MGI
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
19223390 MGI
acts upstream of or within neural tube development IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of or within neural tube formation IMP
IMP: Inferred from mutant phenotype
11406614 MGI
acts upstream of or within protein localization to cilium IMP
IMP: Inferred from mutant phenotype
28154160 MGI
involved in protein localization to cilium IMP
IMP: Inferred from mutant phenotype
31761534 MGI
acts upstream of or within regulation of G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
28154160 MGI
acts upstream of or within regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19286674 MGI
acts upstream of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19223390 MGI
acts upstream of or within smoothened signaling pathway involved in dorsal/ventral neural tube patterning IMP
IMP: Inferred from mutant phenotype
19223390 MGI
Cellular Component GO Annotation Evidence References Source
located in axoneme IDA
IDA: Inferred from direct assay
19286674 MGI
located in cilium IDA
IDA: Inferred from direct assay
19286674 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubby-related protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15272 TULP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tulp3 NCBI NCBI:7289