Sox21 - SRY (sex determining region Y)-box 21 Gene

Also Known as Sox25

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223227

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within hair follicle development and regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; oral region epithelium; and skin. Orthologous to human SOX21 (SRY-box transcription factor 21). [provided by Alliance of Genome Resources, Apr 2022]

Sox21 Products (1)

mRNA Protein Name
NM_177753.3 NP_808421.1 transcription factor SOX-21

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12446692 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12446692 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12446692 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12446692 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within hair cycle IMP
IMP: Inferred from mutant phenotype
19470461 MGI
acts upstream of or within hair follicle development IMP
IMP: Inferred from mutant phenotype
19470461 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12446692 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12446692 MGI
acts upstream of or within skin development IMP
IMP: Inferred from mutant phenotype
19470461 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor SOX-21

  • DNA-binding protein SOX21

  • HMG-box protein SOX21

  • SRY-box containing gene 21

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13592 SOX21 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18684 Sox10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sox21 NCBI NCBI:11166